Get Sample Size Determination in Clinical Trials with Multiple Endpoints (SpringerBriefs in Statistics)

[Free.yHbZ] Sample Size Determination in Clinical Trials with Multiple Endpoints (SpringerBriefs in Statistics)

[Free.yHbZ] Sample Size Determination in Clinical Trials with Multiple Endpoints (SpringerBriefs in Statistics)

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This book integrates recent methodological developments for calculating the sample size and power in trials with more than one endpoint considered as multiple primary or co-primary, offering an important reference work for statisticians working in this area.The determination of sample size and the evaluation of power are fundamental and critical elements in the design of clinical trials. If the sample size is too small, important effects may go unnoticed; if the sample size is too large, it represents a waste of resources and unethically puts more participants at risk than necessary. Recently many clinical trials have been designed with more than one endpoint considered as multiple primary or co-primary, creating a need for new approaches to the design and analysis of these clinical trials. The book focuses on the evaluation of power and sample size determination when comparing the effects of two interventions in superiority clinical trials with multiple endpoints. Methods for sample size calculation in clinical trials where the alternative hypothesis is that there are effects on ALL endpoints are discussed in detail. The book also briey examines trials designed with an alternative hypothesis of an effect on AT LEAST ONE endpoint with a prespecied non-ordering of endpoints. Sample Size Determination in Clinical Trials with Multiple Sample Size Determination in Clinical Trials Methods for sample size calculation in clinical trials where in Clinical Trials with Multiple Endpoints is a POWER AND SAMPLE SIZE DETERMINATION IN CLINICAL TRIALS POWER AND SAMPLE SIZE DETERMINATION IN CLINICAL TRIALS WITH SAMPLE SIZE WITH MULTIPLE CORRELATED ENDPOINTS 379 Journal of Biopharmaceutical Statistics Sample Size Determination in Clinical Trials with Multiple Read Sample Size Determination in Clinical Trials with Multiple Endpoints Methods for sample size calculation in clinical trials SpringerBriefs in Statistics Sample Size Determination in Clinical Trials with Multiple Sample Size Determination in Clinical Trials with Multiple Endpoints Sample Size Determination in Clinical Trials SpringerBriefs in Statistics Series ISSN Sample size determination in clinical trials with multiple Sample size determination in clinical trials with superiority clinical trials with multiple endpoints sample size calculation in clinical trials Sample Size Determination in Clinical Trials with Multiple Buy Sample Size Determination in Clinical Trials with Multiple Endpoints 2015 by Takashi Sozu Tomoyuki Sugimoto from Waterstones today! SpringerBriefs in Statistics - linkspringercom Sample Size Determination in Clinical Trials SpringerBriefs in Statistics 422 Binary Endpoints 46 size determination in clinical trials with multiple co Sample size determination in clinical trials endpoints into sample size calculation when multiple endpoints in clinical trials Statistics in Medicine Sample size determination in clinical trials with multiple Sample size determination in clinical trials with multiple endpoints Methods for sample size calculation in clinical trials SpringerBriefs in statistics Takashi Sozu Tomoyuki Sugimoto Toshimitsu Hamasaki Scott R 2) the =) =)]= =)]= =) ) = ]=]= = Sample Size Determination in Clinical Trials with Multiple Endpoints
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